Palestinians in Gaza say they were fired on once again as they headed to one of the aid distribution centres run by the Israeli- and US-backed Gaza Humanitarian Foundation on Monday.
Witnesses said that for the first time they were fired on by Palestinian gunmen near the GHF site in the Tal al-Sultan area of Rafah, in the south. They also said Israeli troops fired on them.
Gaza's Hamas-run health ministry said six people were killed and 99 injured from areas designated for aid collection.
The Israeli military said it was looking into the reports.
The GHF said the Tal al-Sultan site did not open on Monday and that there were no incidents at two other sites which did hand out aid.
It comes days after Israel's prime minister acknowledged that it was arming Palestinian clans in Gaza who were opposed to Hamas.